(A) A substance derived from the Madagascar periwinkle, which has proved useful in decreasing mortality among young leukemia patients,
(B) A derivative, which has proved useful in decreasing mortality among young leukemia patients, of the Madagascar periwinkle,
(C) A Madagascar periwinkle derivative, which has proved useful in decreasing mortality among young leukemia patients,
(D) The Madagascar periwinkle has a derivative which has proved useful in decreasing mortality among young leukemia patients, that
(E) The Madagascar periwinkle, a derivative of which has proved useful in decreasing mortality among young leukemia patients,
Solution:
Modifier + Logic*
Understanding correct meaning is important here. What has proven to be useful is the derived substance and not the Madagascar periwinkle itself. Also, what is cultivated is Madagascar periwinkle and not its derivative.
Hence, A can be eliminated as it implies that Madagascar periwinkle has proven to be useful.
B and C are incorrect as they suggest that the derivative is cultivated.
D can be eliminated due to incorrect usage of that.
E is the best choice here.
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